Novel biological activity of ameloblastin in enamel matrix derivative

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Novel biological activity of ameloblastin in enamel matrix derivative

OBJECTIVE Enamel matrix derivative (EMD) is used clinically to promote periodontal tissue regeneration. However, the effects of EMD on gingival epithelial cells during regeneration of periodontal tissues are unclear. In this in vitro study, we purified ameloblastin from EMD and investigated its biological effects on epithelial cells. MATERIAL AND METHODS Bioactive fractions were purified from...

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The Use of Enamel Matrix Derivative

Background—Periodontal disease results in the loss of the attachment apparatus. In the last three decades, an increasing effort has been placed on seeking procedures and materials to promote the regeneration of this tissue. The aim of this paper is to evaluate the effect of enamel matrix derivative (EMD) during regenerative procedures. In addition, a meta-analysis is presented regarding the cli...

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Success Evaluation of Pulpotomy in Primary Molars with Enamel Matrix Derivative: a Pilot Study

Aim: To investigate the effect of Emdogain gel (EMD) in pulpotomized primary molars and its clinical and radiographic outcomes. Methods and Materials: In this   study, 18 lower second primary molars of nine children were treated by   pulpotomy. The teeth were randomly assigned to the EMD (experimental) and Formocresol (control) groups in each patient (split mouth). Following removal of the coro...

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Root coverage technique with enamel matrix derivative.

Various periodontal plastic surgical techniques are employed in obtaining root coverage. Recently, the use of an enamel matrix derivative (EMD) has been reported in such treatment. We report 2 cases of root coverage surgery with a coronally positioned flap in combination with EMD (CPF+EMD) and connective tissue graft in combination with EMD (CTG+EMD). Case 1: The patient was a 25-year-old woman...

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Evaluation of Enamel Matrix Derivative (EMD) Teratogenicity on the Rat Embryo Neural Crest Culture

Enamel matrix derivative Emdogain (EMD) is widely used in periodontal treatment in spite of the fact that its effect on the developing embryo has not been elucidated. The aim of this study was to investigate the teratogenic effect of EMD on the rat embryo neural crest cells. The neural crest is a unique population of cells that migrates from the dorsal neural tube along defined pathways and pro...

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ژورنال

عنوان ژورنال: Journal of Applied Oral Science

سال: 2015

ISSN: 1678-7757

DOI: 10.1590/1678-775720140291